627-42-9, Adding some certain compound to certain chemical reactions, such as: 627-42-9, name is 2-Methoxyethyl chloride, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 627-42-9.
Adding 76.1 g (0.5 mol) of methyl salicylate to 250 ml of N-methylpyrrolidone,2-chloromethyl ethyl ether 56.7 g (0.6 mol),Potassium iodide 8.3g (0.05mol),Potassium carbonate 82.9g (0.6mol),It was stirred at 120 C for 16 hours.After cooling the reaction solution, 300 ml of water was added,Extracted with 300 ml of ethyl acetate,After washing the ethyl acetate solution with saturated brine,The solvent was distilled off. Thereafter, 40 g of a 50% aqueous NaOH solution, 40 ml of water, and 40 ml of ethanol were added.It was stirred at 100 C for 1 hour.After the reaction is completed, hydrochloric acid water is added for neutralization.Ethyl acetate was added for extraction.The ethyl acetate solution is washed with saturated brine.The solvent was distilled off. Thereafter,Purification by ruthenium column chromatographyAnd get 59g(yield 60%)Intermediate 4.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 627-42-9.
Reference:
Patent; Fujifilm Corporation; Takasaki, Yuta; Sasaki, Daisuke; Ishizaka, Soji; (141 pag.)TWI626233; (2018); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics