13078-79-0, name is 2-(3-Chlorophenyl)ethanamine, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 13078-79-0
To a solution of 13 (40.0mg, 0.09mmol) in 5mL of CH2Cl2 was added the respective amine and the reaction mixture was stirred for 4hat room temperature and N2 atmosphere. Water (20mL) was added to the reaction mixture and the layers were separated. The aqueous layer was extracted with CH2Cl2 (3¡Á40mL), the combined CH2Cl2 layers were washed with water (30mL), dried over anhydrous Na2SO4, filtered and the solvent was removed under vacuum to get the crude product that was purified by preparative TLC (CH2Cl2/MeOH 20:1) to give the urea product.
Statistics shows that 13078-79-0 is playing an increasingly important role. we look forward to future research findings about 2-(3-Chlorophenyl)ethanamine.
Reference:
Article; Figueiredo, Sandra A.C.; Salvador, Jorge A.R.; Cortes, Roldan; Cascante, Marta; European Journal of Medicinal Chemistry; vol. 138; (2017); p. 422 – 437;,
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