Introduction of a new synthetic route about 932-32-1

According to the analysis of related databases, 932-32-1, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 932-32-1, name is 2-Chloro-N-methylaniline, This compound has unique chemical properties. The synthetic route is as follows., name: 2-Chloro-N-methylaniline

General procedure: A suspension of N-arylglycine ester 1 (0.5 mmol), N-substituted anilines 2 (0.6 mmol) and Methylene blue (0.025 mmol) in CH3CN was stirred for 24 h at 50 C under an air atmosphere irradiated by blue lights. After cooling, water (10 mL) was added and the mixture was extracted with CH2Cl2 (3 x 10 mL). The combined organic layer was dried over anhydrous sodium sulfate and then concentrated under reduced pressure. The residues were purified by flash column chromatography (n-hexane-EtOAc) to afford the desired product 3.

According to the analysis of related databases, 932-32-1, the application of this compound in the production field has become more and more popular.

Reference:
Article; Sun, Bin; Deng, Jiacheng; Li, Deyu; Jin, Can; Su, Weike; Tetrahedron Letters; vol. 59; 49; (2018); p. 4364 – 4369;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics