Application of 932-96-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 932-96-7 name is 4-Chloro-N-methylaniline, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: The reaction was carried out in a 10-mL stainless steel autoclave which was coupled with a magnetic stirrer. In a typical experiment for the N-formylation of amines with CO2 and hydrosilanes, N-methylaniline, the catalyst 3-PSZ-Br (or other catalysts when performing comparisons), and phenylsilane were added into the reactor. Subsequently, CO2 was charged into the reactor until the pressure reached 0.5 MPa and the reactor was then heated by an oil bath to 40 C while being stirred continuously. After the reaction, the autoclave was quickly cooled to 0 C and depressurized to atmospheric pressure [14]. The cycloaddition reactions with epoxides and CO2 were carried out in a similar fashion. Conversions and yields were determined using naphthalene or biphenyl as the internal standard and measured by a gas chromatograph (GC2010, Shimadzu Corporation, Japan) equipped with a capillary column (Rtx-5, 30 m ¡Á 0.32 mm ¡Á 0.25 mum) and a flame ionization detector (FID). The structure and the purity of the corresponding products were identified by 1H NMR, 13C NMR, and GC-MS analysis.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-Chloro-N-methylaniline, and friends who are interested can also refer to it.
Reference:
Article; Zhang, Wuying; Luo, Rongchang; Xu, Qihang; Chen, Yaju; Lin, Xiaowei; Zhou, Xiantai; Ji, Hongbing; Cuihua Xuebao/Chinese Journal of Catalysis; vol. 38; 4; (2017); p. 736 – 744;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics