Synthetic Route of 1940-27-8, A common heterocyclic compound, 1940-27-8, name is 4-Bromo-2,5-dichloroaniline, molecular formula is C6H4BrCl2N, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of compound (III) (4.2 mmol), the appropriate amine (4.2 mmol) and triethylamine (8.4mmol) in dry acetonitrile was refluxed for 3 hr. The mixture was cooled, poured on crushed ice and filtered. The residue was washed with cold water and dried. The crude product was recrystallized from ethanol to get the titled compounds.
The synthetic route of 1940-27-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Pradeep Kumar; Joshi, Shrinivas D.; Dixit, Sheshagiri R.; Kulkarni; Indian Journal of Heterocyclic Chemistry; vol. 25; 1; (2015); p. 37 – 44;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics