Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 20850-43-5, name is 5-(Chloromethyl)benzo[d][1,3]dioxole, A new synthetic method of this compound is introduced below., Recommanded Product: 5-(Chloromethyl)benzo[d][1,3]dioxole
4- (1,3_-benzodioxol-dioxan-5-methoxy) -2_ hydroxyacetophenone Synthesis[0078] In a 500mL three-necked flask, 3.0g (0.02mol) 2 , 4-hydroxyacetophenonewas dissolved in 150mL acetone, 0.8gKI, 2.0gK 2C03, a small amount of the TBAB,heated to reflux with stirring, slowly added dropwise containing 3.14g(0.02mol) 5_-chloro-methyl-1, 3 – benzodioxol dioxane acetone 150mL. Afterthe dropwise addition, it was refluxed for one hour, cooled, filtered offsolid, and concentrated to give a pale yellow solid which was recrystallizedfrom ethanol to give white needle crystals, 4.0g,
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Southeast University; Chi, Jin; Ji, min; (19 pag.)CN103539760; (2016); B;,
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