Related Products of 56961-77-4,Some common heterocyclic compound, 56961-77-4, name is 1-Bromo-2,3-dichlorobenzene, molecular formula is C6H3BrCl2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
In a nitrogen atmosphere, a flask containing 60 N1,N1,N3-triphenylbenzene-1,3-diamine (20.0 g), 44 1-bromo-2,3-dichlorobenzene (6.4 g), Pd-132 (0.2 g), 45 NaOtBu (6.8 g), and 28 xylene (70 ml) was heated and stirred at 120 C. for two hours. The reaction liquid was cooled to room temperature. Thereafter, 30 water and 40 ethyl acetate were added thereto, and the resulting mixture was partitioned. Subsequently, purification was performed by silica gel column chromatography (eluent: toluene/heptane=4/6 (volume ratio)) to obtain 88 N1,N1?-(2-chloro-1,3-phenylene) bis(N1,N3,N3-triphenylbenzene-1,3-diamine) (15.0 g).
The synthetic route of 56961-77-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; JNC CORPORATION; FUJITA, Yukihiro; (228 pag.)US2019/165279; (2019); A1;,
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