Analyzing the synthesis route of 51572-93-1

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 51572-93-1.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 51572-93-1, name is O-(2,4-Dichlorobenzyl)hydroxylamine hydrochloride, This compound has unique chemical properties. The synthetic route is as follows., Formula: C7H8Cl3NO

General procedure: A mixture of 7 (2.5 mmol), alkoxyamine hydrochloride (2.8 mmol), andpyridine (10 mL) was stirred at room temperature for 16 h, concentrated to 2 mL at reducepressure, poured into water (20 mL), and then extracted with methylene chloride (3 ¡Á20 mL). The combined organic layer was washed with dilute hydrochloride acid, waterand brine successively, dried over sodium sulfate. After evaporating the solvent, the crudeproduct was purified by silica gel column chromatography (petroleum:ethyl acetate=30:1)to give a mixture of Z and E isomers of 2. Among them, 2b, 2f, and 2j were further purifiedby silica gel column chromatography (petroleum:ethyl acetate = 2000:1) to give their Zand E isomers.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 51572-93-1.

Reference:
Article; Meng, Chen; Li, Jian-Jun; Liang, Xiao-Mei; Zhang, Jian-Jun; Wang, Dao-Quan; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 189; 10; (2014); p. 1529 – 1538;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics