Electric Literature of 106-39-8, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 106-39-8 as follows.
General procedure: CS2 (1.3 mmol, 0.07 mL) was added to a stirred solution of KCN (1.1 mmol, 0.07 g) in DMF (1 mL) at room temperature. After 15 min, bromobenzene (1.0 mmol, 0.10 mL), K2CO3 (1.0 mmol, 0.14 g) and CuI (20 mol%, 0.038 g) were added and the mixture stirred at 120 C. Upon reaction completion (TLC, 6.5 h), the mixture was cooled to room temperature, diluted with H2O (1 mL), and extracted with n-hexane/ethyl acetate (1:1, 4 ¡Á 1 mL). The combined organic extracts were concentrated and the residue purified by silica gel column chromatography using n-hexane as eluent to give the pure diphenyldisulfane in 90% (0.098 g) yield.
According to the analysis of related databases, 106-39-8, the application of this compound in the production field has become more and more popular.
Reference:
Article; Abbasi, Mohammad; Nowrouzi, Najmeh; Borazjani, Saeedeh Ghassab; Tetrahedron Letters; vol. 58; 45; (2017); p. 4251 – 4254;,
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