Application of 20816-79-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20816-79-9, name is 1-Bromo-8-chloronaphthalene, This compound has unique chemical properties. The synthetic route is as follows.
Under a nitrogen atmosphere,the intermediate A-BE, 1-bromo-8-chloronaphthalene, and potassium carbonate were mixed at a molar ratio of 1: (1.0-1.2):3.0 under a nitrogen atmosphere, and added to the catalyst containing palladium acetate and tri-tert-butylphosphine tetrafluoroboratein toluene/water,Under reflux with nitrogen for 12-16h, cooled down, the reaction solution is allowed to stand for liquid separation, dried, and purified by column chromatography to obtain intermediate M-1.
The chemical industry reduces the impact on the environment during synthesis 1-Bromo-8-chloronaphthalene. I believe this compound will play a more active role in future production and life.
Reference:
Patent; CECEP Wanrun Co., Ltd.; Li Qing; Li Zishu; Shi Yu; Meng Fanmin; Zhou Yinbo; Hu Baohua; (17 pag.)CN108586319; (2018); A;,
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