Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 870-24-6, name is 2-Chloroethanamine hydrochloride, This compound has unique chemical properties. The synthetic route is as follows., Formula: C2H7Cl2N
In a IL round bottom flask, 50.4g sodium hydroxide (1.26mol) was dissolved in 50OmL water (-10% solution). 66.6g (.574mol) 2-chloroethylamine hydrochloride was then added and the solution stirred in an ice bath at 0C until the salt was completely dissolved. lOOg (.631mol) 4-fluorobenzoyl chloride was then added dropwise via an addition funnel into the vigorously stirred solution. After addition, the solution stirred at O0C for 1 hour followed by stirring at room temperature for 1 hour. The cloudy mixture was then filtered to remove the water and the solids washed with ether and then filtered to give ~118g crude (slightly wet) benzamide (Alternatively, the solids could be dissolved in methylene chloride, dried with magnesium sulfate, filtered and evaporated to completely remove water from the solids). These solids were recrystallized from 120ml EtOAc/200mL hexanes to give 88.2g crystalline N-(2-chloroethyl)-4-fluorobenzamide after hexanes wash and drying (an additional 6.22g benzamide recrystallized from the original water mother liquor). NMR confirmed the structure of this compound (81.4% total yield).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 870-24-6.
Reference:
Patent; UNIVERSAL DISPLAY CORPORATION; WO2006/121811; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics