Brief introduction of 627-42-9

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 627-42-9.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 627-42-9, name is 2-Methoxyethyl chloride, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 627-42-9

1-chloro-2-methoxyethane (0.48 mol) was added to the mixture ofmethyl 2-hydroxybenzoate (0.40 mol), K2CO3 (0.80 mol), KI(0.04 mol) and DMF (150 mL). The mixture was heated for 6 h at150 C. The solution was cooled and filtered, and the solvent wasevaporated under reduced pressure. The residue was dissolved inCHCl3 and extracted with water and 10% NaOH. The organic phasewas dried over anhydrous MgSO4 and filtered, and the solvent wasevaporated under reduced pressure. Yield: 96%, RF: 0.78 (EtOAc/petroleum ether 1:1).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 627-42-9.

Reference:
Article; Vettorazzi, Marcela; Angelina, Emilio; Lima, Santiago; Gonec, Tomas; Otevrel, Jan; Marvanova, Pavlina; Padrtova, Tereza; Mokry, Petr; Bobal, Pavel; Acosta, Lina M.; Palma, Alirio; Cobo, Justo; Bobalova, Janette; Csollei, Jozef; Malik, Ivan; Alvarez, Sergio; Spiegel, Sarah; Jampilek, Josef; Enriz, Ricardo D.; European Journal of Medicinal Chemistry; vol. 139; (2017); p. 461 – 481;,
Chloride – Wikipedia,
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