13918-92-8, name is 2,4-Difluorobenzene-1-sulfonyl chloride, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 13918-92-8
To a solution of 3 (10 g, 49.25 mmol) in pyridine (50 mL) wasadded benzenesulfonyl chloride 4 (64.03 mmol) slowly under icebath. After adding 4, the mixture was stirred for 18 h at room temperature.The resulting solution was quenched with iced water(500 mL), and stirred at room temperature for 1 h. The mixturewas filtered, and the precipitate was washed with water anddiethyl ether, and dried overnight to afford 5b
The synthetic route of 13918-92-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Chen, Ying; Zhang, Ling; Yang, Chao; Han, Jinsong; Wang, Chongqing; Zheng, Canhui; Zhou, Youjun; Lv, Jiaguo; Song, Yunlong; Zhu, Ju; Bioorganic and Medicinal Chemistry; vol. 24; 5; (2016); p. 957 – 966;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics