Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 14862-52-3, name is 3,5-Dibromochlorobenzene, A new synthetic method of this compound is introduced below., Safety of 3,5-Dibromochlorobenzene
Sub-1-IV-34 (20.98 g, 52.54 mmol) obtained in the above synthesis was dissolved in THF (220 ml) in a round bottom flask and 1,3-dibromo-5-chlorobenzene (CAS Registry Number: 14862-52-3) (21.31 g, 78.81 mmol), Pd (PPh3) 4 (2.43 g, 2.10 mmol), K2CO3 (21.78 g, 157.62 mmol) and water (110 ml) were added and stirred at 80 C. After the reaction was completed, the reaction mixture was extracted with CH 2 Cl 2 and water. The organic layer was dried over MgSO 4 and concentrated. The resulting compound was purified by silicagel column and recrystallized to obtain 14.59 g (yield: 60%) of the product.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Duksan Neolux Co.,Ltd.; So Gi-ho; Cho Hye-min; Lee Yun-seok; Park Hyeong-geun; Park Jong-gwang; Jeong Yeon-seok; Choi Yeon-hui; Lee Jeong-uk; (66 pag.)KR2017/126400; (2017); A;,
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