Related Products of 3972-56-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3972-56-3, name is 1-tert-Butyl-4-chlorobenzene, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: A mixture of the aryl chloride (1 mmol), arylboronic acid (1.5 mmol), Pd(OAc)2 (0.5 molpercent), dre-NHC (0.5 molpercent), K2CO3 (1.5 mmol), in DMF:water (6 mL (1:1)) in a round bottom flask was stirred at the appropriate temperature and indicated time under an air atmosphere. The mixture was added to cold water (10 mL) and extracted with ethyl acetate (2×5 mL). The organic phase was dried with MgSO4 and filtrated through a short on silica gel column. Then volatiles were removed under reduced pressure and yields were determined by GC using undecane as an internal standard. All catalytic reactions were duplicated.
The chemical industry reduces the impact on the environment during synthesis 1-tert-Butyl-4-chlorobenzene. I believe this compound will play a more active role in future production and life.
Reference:
Article; Karaca, Emine Oezge; Akkoc, Mitat; Nawaz Tahir, Muhammad; Ar?c?, Cengiz; ?mik, Fatma; Guerbuez, Nevin; Ya?ar, Sedat; Oezdemir, ?smail; Tetrahedron Letters; vol. 58; 36; (2017); p. 3529 – 3532;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics