Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 60811-21-4, name is 4-Bromo-2-chloro-1-fluorobenzene, A new synthetic method of this compound is introduced below., Recommanded Product: 60811-21-4
Add 2-chloro-1-fluoro-4-bromobenzene (0.10 mol) to a 250 mL round bottom flask and dissolve in DMF (100 mL). Add potassium carbonate (0.20 mol) and di-n-hexylamine (0.10 mol) with stirring. The reaction system was heated to 90 C for 72 hours. After completion of the reaction, the mixture was cooled to room temperature, filtered, and the organic phase was concentrated to 50 mL, poured into dichloromethane (150 mL), washed with water (150 mL¡Á3) and brine (150 mL) The sodium was dried, and the solvent was evaporated under reduced pressure. and the crude material was purified by column chromatography to yield N, N-dihexyl-2-chloro-4-bromoaniline.
The synthetic route of 60811-21-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Ocean University of China; Shao Changlun; (69 pag.)CN108658937; (2018); A;,
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