Application of 2106-04-9, These common heterocyclic compound, 2106-04-9, name is 3-Chloro-2-fluoroaniline, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Will 25g compound 214.5g of compound 3,400 mL of isopropanol was added to the reaction flask.Warming up to reflux for 3 h,After the TLC detection reaction is completed, the temperature is lowered to 0 to 40 C, and suction filtration is performed.Then drying at 40 to 50 C to obtain 35 g of compound 4;
The synthetic route of 2106-04-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Tonghua Normal College; Geng Xiaoyu; Xue Mingxing; Zang Hao; Liu Xuekun; Sun Renshuang; Xue Changsong; Zhang Haifeng; (13 pag.)CN109438423; (2019); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics