Synthetic Route of 39226-95-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 39226-95-4, name is 2,3-Dichlorobenzylamine belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Example 20: Preparation of N-(4,5-dihydrothiazol-2-yl)-N-[1-(2,3-dichlorophenyl)-3- methylbut-3-enyl]amine20.1 Preparation of N-(2,3-dichlorobenzyl)-N-(4,5-dihydrothiazol-2-yl)amineA solution of 2-chloroethyl isothiocyanate (3.45 g) in diethyl ether (20 ml) was added dropwise to a solution of 2,3-dichlorobenzylamine (5.00 g) in diethyl ether(80 ml) at 0 0C and the mixture was allowed to warm up to room temperature over 3 h. An aqueous solution of sodium hydroxide (1 M, 100 ml) was then added and the mixure was further stirred for 1 h. After seperation of the phases, the organic phase was washed with water, dried over sodium sulfate and concentrated in vacuo. The residue was purified by column chromatography to yieldN-(2,3-dichlorobenzyl)-N-(4,5-dihydrothiazol-2-yl)amine.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,3-Dichlorobenzylamine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; BASF SE; WO2009/115491; (2009); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics