Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 7051-16-3, name is 1-Chloro-3,5-dimethoxybenzene, A new synthetic method of this compound is introduced below., category: chlorides-buliding-blocks
1-chloro-3,5-dimethoxybenzene (10.0 g, 58 mmol) and N-bromosuccinimide (10.3 g, 58 mmol)In 1,2-diethylene chloride (200 ml)After melting, the mixture is stirred at room temperature for 24 hours.After the reaction, the solvent was removed from the reaction solution through a rotary evaporator,After extraction with methylene chloride / distilled water, column chromatography was carried out using a methylene chloride / hexane mixed solvent as a developing solvent to obtain 13.3 g of intermediate 1
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; LG Chem, Ltd.; Dankook University Cheonan Campus Industry-Academic Cooperation Foundation; Gu Gi-dong; Lee Gi-gon; Keum Su-jeong; Kim Gong-gyeom; Lee U-cheol; Lee Chil-won; Cha Jae-ryeong; Joo Yun-seok; (37 pag.)KR2019/109846; (2019); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics