Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 707-36-8, Name is 1-Chloro-3,5-dimethyladamantane, SMILES is CC1(C2)CC3(C)CC2(Cl)CC(C3)C1, belongs to chlorides-buliding-blocks compound. In a document, author is Luo, Weifang, introduce the new discover, SDS of cas: 707-36-8.
A two-photon multi-emissive fluorescent probe for discrimination of Cys and Hcy/GSH via an aromatic substitution-rearrangement
Cys (Cysteine), Hcy (homocysteine), and GSH (glutathione) are three important kinds of biothiols, playing crucial roles in the variety of pathological and physiological processes. It is greater challenges to simultaneously identify different biothiols due to their similar molecular structures and chemical characteristics. In this work, we employed a multi-emissive fluorescent probe by sulfonyl benzoxadiazole (SBD) with halogen chloride unit as the interaction site based on aromatic substitution-rearrangement strategy to discriminate Cys and Hcy/GSH. The response of probe 1 to Cys would generate FRET and cause a red-shift of fluorescence emission, while Hcy/GSH only lead to different degrees of fluorescence enhancement owing to PET. The probe showed good selectivity, high sensitivity, and low detection limits to three biothiols (Cys: 0.86 mu M, Hcy: 0.48 mu M and GSH: 0.54 mu M). Such capability of the probe could be demonstrated to successfully quantitatively detect the concentrations of Cys/ Hcy/GSH in human plasmas. In addition, the probe was also successfully applied for imaging biothiols in lysosomes and real-time monitoring GSH changes in living cells through two-photon fluorescence microscopy.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 707-36-8 is helpful to your research. SDS of cas: 707-36-8.