The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Quality Control of 3-Chloro-N,N-dimethylpropan-1-amine hydrochloride, 5407-04-5, Name is 3-Chloro-N,N-dimethylpropan-1-amine hydrochloride, SMILES is CN(C)CCCCl.[H]Cl, in an article , author is Karahan, Gokhan, once mentioned of 5407-04-5.
The aim of the present study was to investigate the effect of dexpanthenol on nerve healing following neurorrhaphy in lacerated peripheral nerves. A total of 30 mature Sprague Dawley rats were used. Surgical sciatic nerve dissection and repair was performed on an experimental group of 20 rats. The remaining 10 rats were designated as the control group. The experimental group was divided into 2 subgroups. The surgery + saline group (SSLE; n=10) was given 1 ml/kg 0.9% sodium chloride saline intraperitoneally. The surgery + dexpanthenol group (SDPL; n=10) rats were given 500 mg/kg/day dexpanthenol intraperitoneally. Histological evaluation of the sciatic nerve tissue revealed that the fibrosis score was significantly lower in the SDPL group than in the SSLE group (P<0.001). Electrophysiological evaluation of compound muscle action potential (CMAP) indicated that the CMAP level in the SDPL group was significantly higher than that of the SSLE group (P<0.001), and the CMAP latency period was lower in the SDPL group compared with the SSLE group (P<0.001). In addition, the SDPL group malondialdehyde level was significantly lower than that of the SSLE group (P<0.001). Functional evaluation with an inclined plane test revealed a significant difference between the SSLE (39.6 +/- 5.5 degrees) and SDPL (79.1 +/- 6.93 degrees) groups (P<0.001). Dexpanthenol was observed to have a positive effect on nerve tissue repaired with neurorrhaphy in a rat sciatic model of laceration-type injuries similar to those frequently encountered in the clinic. But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 5407-04-5, you can contact me at any time and look forward to more communication. Quality Control of 3-Chloro-N,N-dimethylpropan-1-amine hydrochloride.
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