A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Formula: https://www.ambeed.com/products/874-42-0.html, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 874-42-0, Name is 2,4-Dichlorobenzaldehyde, molecular formula is C7H4Cl2O. In an article, author is Kudva, Narayana U. N.,once mentioned of 874-42-0.
Synthesis of isoxazoline heterocycle containing benzimidazole moiety with the highest bioactivity using substituted benzaldehyde as starting material is reported in this paper. In the beginning, the precursor benzaldehy des were treated with hydroxylamine hydrochloride to afford respective aldoximes. The resultant compound as subjected to cyclization reaction with allyl chloride in the presence of chloramine-T to afford isoxazoline key intermediate. Finally. benzimidazole was subjected to S-alkylation with isoxazoline moiety to afford the title compound with good yield. This method cultivated many advantages like: short reaction time and easy isolation. All the compounds structurally characterized by H-1 NMR, C-13 NMR, LCMS, IR spectral data, and elemental analysis. Besides. all the synthesized compounds ere tested for their antimicrobial and antioxidant activity. The bioactivity was envisioned that the compound 5a and 5f exhibited excellent antifungal activity. which may be helpful in developing a lead to inhibit microbes.
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Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics