Synthetic Route of 204930-37-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 204930-37-0, name is 5-Bromo-1,3-dichloro-2-methylbenzene, This compound has unique chemical properties. The synthetic route is as follows.
Preparation 3; 5-bromo-2-(bromomethyl)- 1 ,3-dichlorobenzene; Heat a solution of 5-bromo-l,3-dichloro-2-methylbenzene (97 mg, 0.40 mmol),N-bromosuccinimide (76 mg, 0.425 mmol) and benzoyl peroxide (16 mg, 0.06 mmol) in CCl4 (5 mL) to reflux for 3 hours under N2. Cool the reaction to room temperature and concentrate to an orange residue. Purify the residue by silica gel chromatography eluting with hexanes to afford 112 mg (87percent) of the product as white crystals.
The chemical industry reduces the impact on the environment during synthesis 5-Bromo-1,3-dichloro-2-methylbenzene. I believe this compound will play a more active role in future production and life.
Reference:
Patent; ELI LILLY AND COMPANY; WO2007/127763; (2007); A2;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics