In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 928-50-7 as follows. Product Details of 928-50-7
Equipped with a mechanical stirrer, a reflux condenser and a thermometer 1000ml four-necked flask, followed by adding 50g (0.48mol) 5- chloro-1-pentene, 50g (0.27mol) phthalimide potassium salt, triphenyl phosphine bromide 0.25g, 2.5g and 500g of nickel sulfate, hexamethylphosphoric triamide. After the addition was complete, the oil bath was heated to 200 deg.] C, the reaction was kept for 3 hours. After incubation, cooled to room temperature. Filter cake by-product potassium chloride reactions, polymerization inhibitor and a catalyst. Rinsed with acetone 100ml fresh cake combined filtrate and washings. Under reduced pressure using a rotary evaporator, acetone was distilled off spin, hexamethylphosphoric triamide and the excess of 5-chloro-1-pentene. Get 57g red viscous liquid, liquid chromatography measured content of 94.81%, the yield was 98.09%.
According to the analysis of related databases, 928-50-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Yizheng Haifan Chemical Co., Ltd; Zou, Congwei; (9 pag.)CN106008314; (2016); A;,
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