In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 25186-47-4 as follows. Quality Control of 3,5-Dichlorotoluene
(1) device: Referring to Figure 2 to determine the connection of the tubular reactor, the pipeline type is:(3a + 3d) DC-channel+ enhanced hybrid round cake rectangular flat pipe,Pipe diameter and volume based on the flow rate and reaction to determine the residence time,Heat transfer medium for thermal oil.(2) 6.06 g of cobalt acetate and 6.06 g of sodium molybdate were dissolved respectively200ml3,5 – dichloro toluene and200ml acetic acid to form a mixed solution,In this case, n (cobalt acetate): n (3,5-dichlorotoluene) = 0.015: 1,6.06 g of sodium bromide was dissolved in 20% H2O2 to form a H2O2-acetic acid solution, where n (sodium bromide): n (3,5-dichlorotoluene) = 0.015: 1,3,5-dichlorotoluene-acetic acid Solution and andH2O2-acetic acid solution respectively to 8.33ml / min andThe flow rate of 16.67 ml / min was injected into the tubular reactor which was continuously heat-exchanging by the constant current pump, at this time, n (H2O2): n (3,5-dichlorotoluene) = 2:Using the microchannel reactor of Figure 2,The reaction temperature was controlled at 105 C and the residence time was 600 s.The outlet was cooled at 0 C and the reaction quenched with dichloromethane.After GC analysis, 3,5-dichlorotoluene conversion rate of 60.8%The yield of 3,5-dichlorobenzaldehyde was 39.2%.
According to the analysis of related databases, 25186-47-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Changzhou University; Yan Shenghu; Jiang Xin; Zhang Yue; Liu Jianwu; Shen Jiefa; Ma Xiaoming; Chen Daixiang; Gu Shunlin; Ni Fengchao; Li Yanfei; Wang Qiuhong; Chen Mingzhu; Wei Jin; Wu Fei; Zhang Yongchao; (9 pag.)CN106588606; (2017); A;,
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