Reference of 2162-98-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2162-98-3, name is 1,10-Dichlorodecane belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
A mixture of 4-aminopyridine (1.5 g, 15.9 mmol) and 1,10-dichlorodecane (1.61 g, 7.95 mmol) in amyl alcohol (26mL) was stirred and refluxed under N2 for 21 h. After cooling to room temperature, white precipitate formed was filtered off and washed with acetone/water to yield 2.4 h(75%) of APDE-8, which was further purified by crystallization from ethanol [Mp 278-282 C. 1H NMR (500 MHz,DMSO-d6) delta 1.17-1.26 (m, 12 H), 1.70-1.75 (m, 4 H),4.10 (t, 4 H, J = 6.0 Hz), 6.87 (d, 4 H, J = 6.5 Hz), 8.20 (d,4H, J = 6.0 Hz), 8.23 (s, 4 H, NH2). MS m/z 327.1565(M-2Cl)+].
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,10-Dichlorodecane, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Sharma, Arun K.; Krzeminski, Jacek; Weissig, Volkmar; Hegarty, John P.; Stewart, David B.; Journal of Antibiotics; vol. 71; 8; (2018); p. 713 – 721;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics