Adding a certain compound to certain chemical reactions, such as: 697-88-1, name is 4-Bromo-2,6-dichloroaniline, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 697-88-1, Formula: C6H4BrCl2N
REFERENCE EXAMPLE 1 N-(4-bromo-2,6-dichlorophenyl)acrylamide A solution of (4-bromo-2,6-dichlorophenyl)amine (4 g) and acryloyl chloride (1.4 mL) in dichloromethane (10 mL) was stirred overnight at room temperature. To the solution were added water and ethyl acetate at 0 degree. The organic layer was washed with a saturated aqueous solution of sodium bicarbonate and a saturated aqueous solution of sodium chloride, subsequently, dried over an anhydrous magnesium sulfate and then concentrated. The residue was washed with diisopropylether to give the title compound (1.96 g) having the following physical data. TLC: Rf 0.25 (hexane:ethyl acetate=5:1); NMR(CDCl3): delta 7.55 (s, 2H), 7.11 (br, 1H), 6.51-6.44 (m, 1H), 6.40-6.20 (m, 1H), 5.85 (d, J=10.5 Hz, 1H).
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.
Reference:
Patent; Takahashi, Kanji; Sumino, Naoki; Yamamoto, Shingo; Sugitani, Masafumi; Uegaki, Akihiko; Nakatani, Shingo; Matsunaga, Naoki; Inukai, Takayuki; US2007/10529; (2007); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics