452-66-4, name is 4-Chloro-1-fluoro-2-methylbenzene, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Product Details of 452-66-4
4-chloro-2-fluorobenzaldehyde and 5-chloro-2-fluorobenzaldehyde were prepared in an analogous manner from 4-chloro-2-fluorotoluene and 5-chloro-2-fluorotoluene respectively (both supplied by Lancaster Synthesis).
The synthetic route of 452-66-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; The Wellcome Foundation; The Regents of the University of California; US5502073; (1996); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics