Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 104-52-9, name is 3-Phenylpropyl Chloride, A new synthetic method of this compound is introduced below., Formula: C9H11Cl
General procedure: B1eB22, B40 or B48 (1.0 mmol, 1.0equiv) were dissolved in5mLN,N-dimethylformamide (DMF), and sodium azide was addedto the above solution. The reaction system was stirred at roomtemperature or 70 C for 24 h. Then water (30 mL) was added,extracted with ethyl acetate (3 10 mL). The organic phase wascombined, dried over anhydrous Na2SO4, filtered, and concentratedto yield the crude azide substituents N1eN22, N40 and N48, whichwere used for the next step without further purification.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Jing, Lanlan; Wu, Gaochan; Hao, Xia; Olotu, Fisayo A.; Kang, Dongwei; Chen, Chin Ho; Lee, Kuo-Hsiung; Soliman, Mahmoud E.S.; Liu, Xinyong; Song, Yuning; Zhan, Peng; European Journal of Medicinal Chemistry; vol. 183; (2019);,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics