Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 56961-77-4, name is 1-Bromo-2,3-dichlorobenzene, A new synthetic method of this compound is introduced below., Recommanded Product: 56961-77-4
[Intermediate 5-1] 10.1 g of 30.17 mmol was dissolved in 100 mL of xylene, and then NatBuO 60.35 mmol 5.8 gFollowed by stirring at 180 C, followed by the addition of 6.82 g of 30.17 mmol of 1-bromo-2,3-dichlorobenzene and 0.17 g of BTP 0.30 mmol in this order.After 12 h, the reaction was quenched with NH4Cl, extracted with EA, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure.This was columned with EA: Hx to obtain 9.34 g (yield 65%) of 19.61 mmol of [intermediate 5-2].
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; LG Chem, Ltd.; Gu Gi-dong; Yoon Jeong-min; Kim Gong-gyeom; Huh Nan-seul-a; Lee Gi-gon; Keum Su-jeong; (52 pag.)KR2018/112721; (2018); A;,
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