Related Products of 203302-92-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 203302-92-5, name is 3-Bromo-2-chloro-6-fluorotoluene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
2-Chloro-3-bromo-6-fluorotoluene (670 mg, 3 mmol), Cul (143 mg, 0.75 mmol), racemic trans-NN’-dimethylcyclohexane-1,2-diamine (213 mg, 1.5 mmol), and Nal (1.12 g, 7.5 mmol) were added to a sealed tube, degassed and dioxane (6 mL) was then added. The reaction mixture was again degassed, flushed with nitrogen and heated at 110 C. for 72 hours. The reaction mixture was cooled to room temperature, diluted with ethyl acetate and the solid reagents were filtered off. The filtrate was concentrated to afford a residue which was passed through a short silica gel column to provide the desired product.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Bromo-2-chloro-6-fluorotoluene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Ge, Min; He, Jiafang; Lau, Fiona Wai Yu; Liang, Gui-Bai; Lin, Songnian; Liu, Weiguo; Walsh, Shawn P.; Yang, Lihu; US2007/265332; (2007); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics