Synthetic Route of 2687-12-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2687-12-9, name is Cinnamyl chloride belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: To a well-stirred solution of 6a-e (1 mmol) in 4 mL of dry DMF was added the suitable organic halides (5.0-6.0 mmol) followed by K2CO3 (5.0-8.0 mmol) and the reaction mixture was heated at 70-80 C with stirring until the reaction was completed. The progress of the reaction was checked by TLC, which showed the appearance of new spots with higher Rf value than the starting compound. After the completion of the reaction, water was added to it and extracted with dichloromethane, washed successively with water and brine and then dried over anhydrous Na2SO4. The residue after solvent evaporation in vacuo, was purified by silica gel column chromatography (10% EtOAc : hexane). cis-3-pentyl-1,4-diphenyl-3-phenylsulfonyl-beta-lactam 7d
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Cinnamyl chloride, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Bhalla, Aman; Modi, Garima; Yadav, Pooja; Kumar, Pankaj; Bari; Hundal, Geeta; Tetrahedron Letters; vol. 61; 29; (2020);,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics