Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 118-69-4, name is 2,6-Dichlorotoluene, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 2,6-Dichlorotoluene
This Example demonstrates the preparation of 2,6-dichloro-3,5-dinitrotoluene.To a 1 L 4-neck round bottom flask equipped with external ice cooling, mechanical stirrer, addition funnel, N2 inlet, and thermometer was added 118 g (1.872 mmol) fuming nitric acid (d=1.54). With cooling, 745 g (1863 mmol SO3) 20% oleum was added over a period of 30 minutes while maintaining a temperature below 30 C. The acid solution was cooled to 0-5 C. and 150 g (932 mmol) 2,6-dichlorotoluene was slowly added over 2 h while maintaining a temperature below 20 C. When addition was complete, the ice bath was removed and the reaction mixture was slowly allowed to warm to room temperature. It was then heated from room temperature to 110 C. over a time period of 45 min. After 15 min at 110 C., the reaction mixture was allowed to cool to room temperature and then cooled to 5 C. It was then filtered through a glass flitted funnel and washed with 250 mL water followed by 250 mL 10% aqueous NH3 solution to yield a pale yellow crystalline wet cake. A small sample was dried in vacuum and analyzed by both H1-NMR and GC and found to be 99.9% pure. The wet cake (219 g) contained about 201.5 g 2,6-dichloro-3,5-dinitrotoluene and 17.5 g water. The net yield of 2,6-dichloro-3,5-dinitrotoluene amounted to about 86%.
According to the analysis of related databases, 118-69-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; E.I. DU PONT DE NEMOURS AND COMPANY; US2010/160675; (2010); A1;,
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