Synthetic Route of 698-01-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 698-01-1, name is 2-Chloro-N,N-dimethylaniline, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: To a stirred solution of tert-amines in dichloromethane (10 ml), m-chloroperbenzoic acid (70%w/w, 1.5 equiv) was added portion wise at room temperature. The resultant solution wasstirred for 4 h and the progress of reaction was monitored using TLC. After completion, the reaction mixture was directlyloaded on basic alumina column and purified using methanol:chloroform solvent mixture as an eluent. The combined filtrates were concentrated to give corresponding amine N-oxides with approx. 90-95% isolated yield.
The chemical industry reduces the impact on the environment during synthesis 2-Chloro-N,N-dimethylaniline. I believe this compound will play a more active role in future production and life.
Reference:
Article; Gupta, Surabhi; Sureshbabu, Popuri; Singh, Adesh Kumar; Sabiah, Shahulhameed; Kandasamy, Jeyakumar; Tetrahedron Letters; vol. 58; 10; (2017); p. 909 – 913;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics