Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 112-26-5, name is 1,2-Bis(2-chloroethoxy)ethane, This compound has unique chemical properties. The synthetic route is as follows., Safety of 1,2-Bis(2-chloroethoxy)ethane
At a temperature 20 C with stirring, 15.42 g (100 mmol) dimethoxyphenol and 8.42 g (45 mmol) of 1,2- (dichloroethanyl) ethane were added to 100 ml N,N-dimethylformamide, potassium hydroxide was added thereto 6.06g (108mmol), warmed to 153 C, the reaction at 40 h, the solvent was distilled off, the solvent was distilled off can be used directly for the next reaction to give brown Yellow turbid liquid; The above brown turbid liquid is added in 100 ml dichloromethane, filters the insoluble substance, using 50 ml 1 M sodium hydroxide solution washing 3 times, then 50 ml saturated sodium chloride solution (20 C) washing 2 times, water-free magnesium sulfate drying, atmospheric dryness dichloromethane, to obtain yellow oily liquid; To the above-mentioned yellow oily liquid by adding 25 ml ethyl ether, up to 35 C, filtering to remove the insoluble matter, cooling to -15 C, cooling 3 h, liquid layered, taking the upper light yellow solution, cooling to -15 C, cooling 48 h, filtering solution, to obtain 15.26 g of powder of white solid 1,2-bis(2-(2,6-dimethoxyphenoxy)ethoxy)ethane, yield 80.27%, purity 98.42%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 112-26-5.
Reference:
Patent; Xi’an Modern Chemical Institute; Lu Tingting; Lu Xianming; Mo Hongchang; Wang Yinglei; Ji Yueping; Xu Minghui; Gao Fulei; Liu Weixiao; (6 pag.)CN107011128; (2017); A;,
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