In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1205-71-6, name is 4-Chloro-N-phenylaniline belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C12H10ClN
In a 250ml round bottom flask,10-bromobenzo [b] naphtho [2,1-d] furan (12 mmol), copper iodide (15 mmol), potassium tert-butoxide (65 mmol),1,2-diaminocyclohexane (12 mmol)And (4-chloro-phenyl) -phenylamine (12 mmol) were added to dry 1,4-dioxane (100 ml) and refluxed for 48 hours under N2 atmosphere. The obtained intermediate was cooled to room temperature, and added Water was then filtered through a pad of diatomaceous earth while being extracted with dichloromethane, then washed with water, and dried over anhydrous magnesium sulfate. After filtration and evaporation, the crude product was purified by silica gel column chromatography to obtain the intermediate HT002-1.
The synthetic route of 1205-71-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shanghai Tianma Organic Shine Display Co., Ltd.; Zhang Lei; Gao Wei; Niu Jinghua; Dai Wenpeng; Xiao Wenjing; Lu Yan; Zhu Hongyan; (28 pag.)CN110746391; (2020); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics