Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 104-52-9, name is 3-Phenylpropyl Chloride, This compound has unique chemical properties. The synthetic route is as follows., Safety of 3-Phenylpropyl Chloride
6-amino-1-ethylbenzo[cd]indol-2(1H)-one can refer to Example 1. A reaction mixture of 6-amino-1-ethylbenzo[cd]indol-2(1H)-one (100 mg, 0.47 mmol) and (3-chloropropyl)benzene (73 mg, 0.47 mmol) in CH3CN (20 mL) was stirred at rt. K2CO3 (195 mg, 1.41 mmol) was added to the reaction mixture, and stirred at 70 C. for overnight. The reaction mixture was extracted with ethyl acetate (150 mL*2). The organic layer was washed with brine and dried over Na2SO4. The solid was filtered off, and the filtrate was concentrated under reduced pressure. The resulting crude product was purified by silica gel chromatography with petroleum ether/ethyl acetate (5/1, v/v) to yield 1-ethyl-6-((3-phenylpropyl)amino)benzo[cd]indol-2(1H)-one (60 mg, 38%) as a yellow solid. 1H NMR (400 MHz, CDCl3) delta 8.06 (d, J=7.2 Hz, 11H), 7.84 (d, J=8.0 Hz, 1H), 7.63 (t, J=7.6 Hz, 1H), 7.32 (t, J=7.6 Hz, 2H), 7.26-7.04 (m, 3H), 6.77 (d, J=7.6 Hz, 1H), 6.34 (d, J=7.2 Hz, 1H), 4.24 (s, 1H), 3.94 (q, J=7.2 Hz, 2H), 3.30 (t, J=6.8 Hz, 2H), 2.83 (t, J=7.2 Hz, 2H), 2.21-2.03 (m, 2H), 1.36 (t, J=7.2 Hz, 3H).
According to the analysis of related databases, 104-52-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Guangzhou Institutes of Biomediciene and Health, Chinese Academy of Sciences; XU, Yong; XUE, Xiaoqian; ZHANG, Yan; SONG, Ming; (42 pag.)US2018/8574; (2018); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics