14862-52-3, name is 3,5-Dibromochlorobenzene, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C6H3Br2Cl
General procedure: 3-bromo-1H-indole (5.0 g, 0.026 mol), 9H-carbazol-3-ylboronic acid (6.5 g, 0.030 mol), Pd(pph3)4 (1.5 g, 0.0013 mol), potassium carbonate (7.2 g, 0.052 mol) in THF 200 ml was reacted at 65 C for 18 hours. After reaction and cooling the H2O:MC after separation of to (n-Hexane: MC) column purification for 1-1 intermediate that is 5.2 g (71% yield) are obtained. (m/z=282). Intermediates 30-2 (4.0 g, 0.010 mol) 1,3-dibromo-5-chlorobenzene to (2.2 g, 0.008 mol) for inserting and removing manufacturing e.g. in the embodiment 1-(1) the same method used in the synthesis of
The synthetic route of 14862-52-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; P&H tech; Hyeon, Seo Young; Jong, Song Ok; Oh, Hyeon Jin; (92 pag.)KR2015/131700; (2015); A;,
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