Electric Literature of 2687-12-9, A common heterocyclic compound, 2687-12-9, name is Cinnamyl chloride, molecular formula is C9H9Cl, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
In the reaction (r-1 ‘), a benzene derivative (3A’) (15.2 g, 0.1 mol) and triethyl phosphite represented by the chemical formula (B) (25 g, 0.15 mol ), And the mixture was stirred at 180 C. for 8 hours and then cooled to room temperature. Thereafter, unreacted or remaining triethyl phosphite was distilled off under reduced pressure to obtain a phosphonate derivative (3C ‘) as a white liquid. The yield from the benzene derivative (3A ‘) of the phosphonate derivative (3C’) was 23.5 g (yield: 92 mol%).
The synthetic route of 2687-12-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Kyocera Document Solutions Co., Ltd.; Okada, Hideki; Sugai, Akio; Kojima, Kensuke; (52 pag.)JP2017/114808; (2017); A;,
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