Application of 870-24-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 870-24-6, name is 2-Chloroethanamine hydrochloride belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
2-Chloroethanamine hydrochloride (4.6 g, 40 mmol), NEt3 (18 mL, 132 mmol) And 50 mL of methylene chloride. The reaction was stirred at room temperature and trimethylchlorosilane (90 mmol, 9.8 g, 11.4 mL) in dichloromethane (20 mL) was added to the system. The reaction was stirred at room temperature overnight. After the reaction was completed, excess triethylamine, trimethylchlorosilane and methylene chloride were removed under reduced pressure. To the resulting residue was added 60 mL of n-hexane. The reaction was stirred at room temperature for 30 minutes and filtered to remove NEt3.HCl. After the filtrate is concentrated, The target product was obtained by distillation under reduced pressure (6.0 g, 68%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Chloroethanamine hydrochloride, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Tsinghua University; Liu Qiang; Fu Shaomin; Shao Zhihui; Wang Yujie; (20 pag.)CN107445995; (2017); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics