Extended knowledge of 104-11-0

The synthetic route of 104-11-0 has been constantly updated, and we look forward to future research findings.

104-11-0, name is 1-(4-Chlorophenyl)-N-methylmethanamine, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. name: 1-(4-Chlorophenyl)-N-methylmethanamine

REFERENTIAL EXAMPLE 2 Dissolved in toluene was 3.1 g (0.02 mole) of 4-chloro-N-methyl-benzylamine, followed by an addition of a catalytic amount of pyridine and a further dropwise addition of 1.8 g (0.022 mole) of diketene at room temperature. After stirring the reaction mixture at room temperature for 3 hours, it was poured in water and then extracted with toluene. Subsequent to purification, N-methyl-N-(4-chlorobenzyl)acetamide was obtained in an oily form.

The synthetic route of 104-11-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Kumiai Chemical Industry Co., Ltd.; Toyo Jozo Co., Ltd.; US4736038; (1988); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics