Related Products of 4090-55-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4090-55-5 name is 2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
BODIE was obtained by the reaction of ethylenediamine with DOPC in trichloromethane.The DOPC (193.79 g, 1. 05 mol) and triethylamine (151.79 g, 1.5 mol)mixture with trichloromethane (200 mL) was put into a dry, four-necked flask equipped asdescribed above. The ethylenediamine (30 g, 0.5 mol) dissolved in trichloromethane(50 mL) was added dropwise at 0-5 C. After the addition, the temperature was increasedslowly to the reflux temperature and then the reaction was stopped after refluxing for 4 h.The resulting white precipitate was filtered and washed with cold distilled water and thendried overnight. The white product (BODIE) was obtained with a yield of 94 %. The massfraction purity of BODIE is 99 % measured by HPLC.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide, and friends who are interested can also refer to it.
Reference:
Article; Han, Feng; Pei, Liangjun; Xue, Fengfeng; Li, Dong; Journal of Solution Chemistry; vol. 45; 8; (2016); p. 1146 – 1157;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics