Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20850-43-5, name is 5-(Chloromethyl)benzo[d][1,3]dioxole, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C8H7ClO2
Example 64: Synthesis of 3-(benzo[d][1 ,3]dioxol-5-ylmethyl)thiazolidine-2,4-dione; A suspension of thiazolidine-2,4-dione (10.0 mmol, 1.17 g), 5- (chloromethyl)benzo[d][1 ,3]dioxole (10.0 mmol, 50% soln in CH2CI2) and potassium fluoride (10.0 mmol, 0.581 g) is stirred at room temperature overnight. The solvent is removed under reduced pressure and the residue dissolved in H2O (50 ml_) and extracted into dichloromethane (3 x 20 ml_). Combined organic fractions were dried over Na2SO4 and the solvent removed under reduced pressure. The obtained oily product is washed with diethyl ether to give 1 .590 g (64%) of 3-(benzo[d][1 ,3]dioxol-5-ylmethyl)thiazolidine-2,4-dione as a white precipitate.
According to the analysis of related databases, 20850-43-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; LEK PHARMACEUTICAL D.D.; WO2008/43733; (2008); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics