Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 6940-78-9, name is 1-Bromo-4-chlorobutane, A new synthetic method of this compound is introduced below., Recommanded Product: 1-Bromo-4-chlorobutane
To a solution of 7-Hydroxy-3,4-dihydrocarbostyril (100 g) and 1-Bromo-4-chlorobutane (245 g) in N,N-Dimethylformamide (500 ml) potassium carbonate (100 g) was added and stirred for 10-15 hours at ambient temperature. After completion of the reaction water (1500 ml) and Toluene (500 ml) was added and stirred. The organic layer was separated and evaporated to dryness to give residue. Cyclohexane (1000 ml) was added to the residue and stirred and filtered to give 7-(4-Chlorobutoxy)-3,4-dihydrocarbostyril (Yield 90% and HPLC purity 97%).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; PHARMATHEN S.A.; KOFTIS, Theocharis, V.; SONI, Rohit, Ravikant; ACHARYA, Hitarth, Harshendu; PATEL, Kandarpkumar, Hasmukhbhai; AHIRRAO, Manoh, Devidas; WO2013/20672; (2013); A1;,
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