Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 6781-98-2, name is 2-Chloro-1,3-dimethylbenzene, A new synthetic method of this compound is introduced below., Product Details of 6781-98-2
General procedure: A test tube was charged with aryl chlorides (0.5 mmol, 1 eq), arylboronic acid (0.75 mmol, 1.5 eq), K3PO4 (1 mmol, 2 eq), H2O (0.5 mL), isopropanol (0.5 mL) and catalyst (0.0005-0.001 mmol) and the mixture was then stirred at room temperature. After the reaction was finished, the mixture was extracted three times with CH2Cl2 (3 x 2mL), dried over Na2SO4, filtered, and the solvent was removed under vacuum. Further purification of the product was achieved by flash chromatography on a silica gel column.
The synthetic route of 6781-98-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Liu, Guiyan; Liu, Chengxin; Han, Fangwai; Wang, Zhongliang; Wang, Jianhui; Tetrahedron Letters; vol. 58; 8; (2017); p. 726 – 731;,
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