Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 4535-90-4, name is 2-Chloro-N-methylethanamine hydrochloride, A new synthetic method of this compound is introduced below., COA of Formula: C3H9Cl2N
A suspension of N-Methyl-2-chloroethylammonium chloride (10 gm) in POCl3 (40 ml) was refiuxed (1350C) over night. After removing excess POCl3 under vacuum product 5i was distilled out under vacuum as light yellow oil and analyzed by 1H and 31P NMR spectroscopy to be pure.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; THRESHOLD PHARMACEUTICALS, INC.; WO2007/2931; (2007); A2;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics