In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3972-56-3, name is 1-tert-Butyl-4-chlorobenzene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 1-tert-Butyl-4-chlorobenzene
1000 g (5.93 mol) of 4-tert-butylchlorobenzene was dissolved in 250 g of 1,2-dichloroethane.A 4-tert-butylchlorobenzene solution was prepared.2000 g (20 mol) of 95%-98% sulfuric acid was added dropwise to 643 g (10 mol) of 95%-98% nitric acid dissolved in a 2 liter three-necked flask kept in an ice water bath to prepare a mixed acid of nitric acid sulfuric acid. .First nitrification reaction:According to the molar ratio of 4-tert-butylchlorobenzene to nitric acid 1:1.2, the reaction temperature is 60-80 C, the flow rate of 4-tert-butylchlorobenzene is 2.5 mL/min, the mixed acid flow rate is 2.6 mL/min, part of 4-un The mixed acid of the butylchlorobenzene solution and the nitric acid sulfuric acid is pumped through the continuous flow microreactor, which comprises a separate fluid module connected in sequence, specifically an inlet mixing reaction module,8 resident modules and one exit module, as described above.Each individual fluid module was maintained at a constant reaction temperature with a reaction residence time of 164 s.The nitration mixture obtained by the reaction is passed through a water separator to separate the first spent acid and the first nitration mixture.
The synthetic route of 3972-56-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shandong Heroic Chemical Co., Ltd.; Wang Yuanchao; Li Rixiang; Yang Anming; Lu Xiao; Ren Miaomiao; Zhang Yingjie; (19 pag.)CN109970566; (2019); A;,
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