Related Products of 1435-50-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1435-50-3, name is 2-Bromo-1,4-dichlorobenzene belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
25.4 g of 2-bromo-1,4-dichlorobenzene, 8.9 ml of iodoethane and 13.3 ml of DMPU are dissolved in 230 ml of THF, and a solution of 16.2 g of lithium tetramethylpiperidide in THF is added dropwise at -70 C. After a further 2 h at -70 C., the reaction mixture is allowed to warm to ambient temperature, and the batch is hydrolysed using water and worked up by extraction. The crude product is purified by fractional distillation. [0126] b.p.: 73 C./0.1 bar. Colourless liquid.
The synthetic route of 2-Bromo-1,4-dichlorobenzene has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK PATENT GMBH; Reiffenrath, Volker; Jasper, Christian; Manabe, Atsutaka; Montenegro, Elvira; Pauluth, Detlef; US2013/221274; (2013); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics