Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 627-42-9, name is 2-Methoxyethyl chloride, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C3H7ClO
Compound 5 (4.1 mL, 44.7 mmol) was added to and mixed with a first mixture including isovanillin (4.0 g, 26.3 mmol), potassium carbonate (6.5 g, 47.3 mmol), and dimethylformamide (DMF, 30 mL) to obtain a second mixture. The second mixture was then stirred at a temperature ranging from 85 C. to 90 C. for 20 hours, cooled to room temperature, and filtered via Buechner funnel, and the residue was washed with EtOAc. The EtOAc filtrate was washed with a sodium hydroxide aqueous solution (2N), water, and brine, and then dried over MgSO4, and concentrated to obtain a yellow oil (5.3 g, 97% yield). The spectrum analysis for the yellow oil obtained by the above procedures is: 1H NMR (400 MHz, CDCl3), delta (ppm): 9.83 (s, 1H), 7.47-7.42 (m, 2H), 6.97-6.95 (d, J=8.2 Hz, 1H), 4.23-4.21 (m, 2H), 3.93 (s, 3H), 3.81-3.79 (m, 2H), 3.44 (s, 3H); 13C NMR (100.6 MHz, CDCl3), delta (ppm): 190.7, 154.9, 148.8, 129.9, 126.8, 110.8, 110.7, 70.6, 68.2, 59.0, 56.0; LRMS-EI+ (m/z): 211 ([M+H]+, 13), 210 ([M]+, 100), 152(67), 123(4), 95(3), 77 (5), 59 (67); HRMS-TOF-ES+ (m/z): [M+H]+ calculated for C11H15O4, 211.0970, found: 211.0971. The yellow oil obtained was confirmed to be Compound 6 (4-methoxy-3-(2-methoxyethoxy)benzaldehyde).
According to the analysis of related databases, 627-42-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; National Chiao Tung University; Chao, Jui-I; Chen, Chin-Piao; Liu, Kuang-Kai; (16 pag.)US10251886; (2019); B1;,
Chloride – Wikipedia,
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