In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2687-12-9, name is Cinnamyl chloride belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Safety of Cinnamyl chloride
General procedure: To a solution of [Ru(Cp*)Cl2]2 (1) (6.2 mg, 1.5 mol%) and K2CO3 (226 mg, 1.63 mmol) in dry acetonitrile (0.5 mL) in a schlenk tube was added cinnamyl chloride (92 mul, 0.65 mmol). The resulting mixture was stirred at room temperature under a nitrogen atmosphere for 20 min followed by a slow addition of the corresponding phenols (0.98 mmol) (Table 2) in dry acetonitrile (1 mL) over 15 minutes. The reaction mixture was stirred for another 16 h at room temperature and then filtered through a celite plug and washed with dichloromethane (10 mL). The filtrate was evaporated under reduced pressure and purified by silica gel column chromatography to afford the branched product. Characterization data and copies of NMR spectra were provided below
The synthetic route of 2687-12-9 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Siddappa, Ravi Kumara Guralamatta; Chang, Chih-Wei; Chein, Rong-Jie; Tetrahedron Letters; vol. 55; 5; (2014); p. 1031 – 1035;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics